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    neuroblastoma RAS viral (v-ras) oncogene homolog

    Background:  

    This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and 

    the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the 

    ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a 

    guanine nucleotide-exchange factor and inactivated by a GTPase activating protein.